Effects of Continuous Infusion of Intravenous Nefopam on Postoperative Pain and Opioid Consumption After VATS

• Status: Not yet recruiting
• Trial end date: 2021-05-30
• Target enrollment: 0
• Participant gender: All

Summary

This prospective, randomized, double-blinded study is designed to evaluate the postoperative analgesic effect of the continuous infusion of intravenous nefopam in patients undergoing video-assisted thoracic surgery (VATS). We hypothesize that the continuous infusion of intravenous nefopam can significantly reduce postoperative opioid consumption and pain severity in patients with VATS.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Collaborator: Pharmbio Korea
• Treatments: Nefopam

Criteria

Inclusion Criteria:

• Patients scheduled to undergo elective unilateral VATS segmentectomy or lobectomy under general anesthesia

• American Society of Anesthesiologists (ASA) physical classification I-II

• Consent to IV-patient controlled analgesia use

• Willingness and ability to sign an informed consent document

Exclusion Criteria:

• Do not understand our study

• Allergies to anesthetic or analgesic medications

• Continuous local anesthetics infiltration for postoperative pain control

• Patients who receive mechanical ventilation more than 2 hours after surgery

• Pregnancy/Breast feeder

• Medical or psychological disease that can affect the treatment response