Overview

Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence

Status:
Completed
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
This study will, in a sample of cocaine-dependent and healthy control subjects, administer corticorelin and compare dopamine release between groups. Dopamine release will be measured using PET neuroimaging with the radiotracer [11C]-(+)-PHNO.
Details
Lead Sponsor:
Centre for Addiction and Mental Health
Treatments:
Adrenocorticotropic Hormone
Cocaine
Corticotropin-Releasing Hormone
Dopamine
Dopamine Agents
Hormones