Effects of Desflurane Versus Propofol on Hemostasis During Splenectomy

• Status: Completed
• Trial end date: 2017-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this prospective randomized study is to evaluate the perioperative effects of inhalational anesthesia (desflurane) and intravenous anesthesia (propofol) on hemostasis in patients undergoing splenectomy with liver cirrhosis guided by the new technology (ROTEM) and the traditional laboratory hemostatic markers.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Theodor Bilharz Research Institute
• Treatments: Desflurane; Hemostatics; Isoflurane; Propofol

Criteria

Inclusion Criteria:

• Patient ASA physical status II and III.

• Age between 22-55 years.

• Child A suffering from pancytopenia.

• Type of surgery: splenectomy

Exclusion Criteria:

• Patients using oral anticoagulants

• Patients using antithrombotic drugs

• Patients using non steroidal anti-inflammatory drugs

• Patients using oral contraceptives

• Age less than 25 or more than 55 years

• Obese patients (body mass index >35 kg m-2)

• Pregnancy and lactation