Effects of Dexmedetomidine on Microcirculation and Residual Kidney Function in Kidney Donors
Status:
Recruiting
Trial end date:
2024-06-01
Target enrollment:
Participant gender:
Summary
Kidney transplant can help patients with end-stage kidney disease to get rid of dialysis and
have a good quality life. However, during the renal donation operation, the stress response
and subsequent inflammatory responses may result in damage to the residual kidney and
transplanted kidney. Dexmedetomidine can increase urine output and decrease the neutrophil
gelatinase associated lipocalin level in patients receiving coronary artery bypass surgery.
The primary goal of this trial is to investigate the effects of perioperative infusion of
dexmedetomidine on the microcirculation and residual kidney function in kidney donors and on
the transplanted kidney function in kidney recipients.