Effects of Dexmedetomidine on Stress Response and Postoperative Analgesia
Status:
Completed
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
Dexmedetomidine is a highly selective α2 adrenoreceptor agonist approved by the US FDA for
short-term postoperative sedation and analgesia.It can also reduce the stress response
without respiratory depression.
In this prospective, randomized, double-blind, placebo-controlled study，we gave
dexmedetomidine or saline placebo 1h before operations were over and assessed the effects of
dexmedetomidine on stress response and postoperative analgesia in patients undergoing
thoracotomy during anesthesia recovery period.