Effects of Different Doses of Aspirin on Pathophysiological Markers in Type 2 Diabetes
Status:
Completed
Trial end date:
2006-07-01
Target enrollment:
Participant gender:
Summary
This study was set up to assess the effects of different doses of aspirin when compared with
placebo (dummy drug), used sequentially over a 2 week study period with a 2 week wash-out
(rest period) in between, in people with type-2 diabetes and high cardiovascular risk.
Specifically, its effects on different factors which are thought to contribute to diabetes
such as insulin resistance (body's ability to effectively use insulin), dysglycaemia (excess
glucose in the blood), oxidative stress (effects from accumulation of by-products of
metabolism), endothelial function (function of lining of blood vessels) and inflammation were
studied.