Effects of Different Vasodilators on Coronary No-reflow During primAry percuTaneous Coronary intErvention in Patients With Acute Myocardial Infarction

• Status: Completed
• Trial end date: 2009-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the efficacy of three different vasodilators including diltiazem, verapamil and nitroglycerin for reversal of no-reflow/slow-flow during direct percutaneous coronary intervention for acute myocardial infarction.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fudan University
• Treatments: Diltiazem; Nitroglycerin; Vasodilator Agents; Verapamil

Criteria

Inclusion Criteria:

• Clinical diagnosis of acute myocardial infarction

• Vessel TIMI flow < grade Ⅲ post-PCI

Exclusion Criteria:

• Heart failure of New York Heart Association (NYHA) class Ⅲ to class Ⅳ

• Sick sinus syndrome

• Atrioventricular block (grade Ⅱ and above)

• SBP ≤ 90mmHg or cardiogenic shock

• Heart Rate ≤60 bpm

• Pregnancy

• Renal or hepatic failure