Effects of Dobutamine on Microcirculation, Regional and Peripheral Perfusion in Septic Shock Patients
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
The investigators hypothesize that dobutamine is able to revert negative redistribution of
flow by inducing a selective vasodilatory effect on hypoperfused territories, particularly at
the sublingual and gastric mucosa, and at the peripheral tissues.
The investigators designed a randomized, cross-over, placebo-controlled study looking at the
acute physiologic effects of 5 mcg/kg/min fixed-dose of dobutamine on cardiac function,
microcirculation, gastric mucosal, hepatosplanchnic, and peripheral perfusion in septic shock
patients.