Effects of Dronedarone on Atrial Fibrillation Burden in Subjects With Permanent Pacemakers
Status:
Terminated
Trial end date:
2012-02-01
Target enrollment:
Participant gender:
Summary
Primary objective was to evaluate the effects of dronedarone on Atrial Fibrillation (AF)
burden (i.e. percent time in AF) as measured on electrogram (EGM) in subjects with a
permanent pacemaker.
Secondary objectives were to evaluate:
- the effects of dronedarone on AF pattern characteristics i.e. ventricular rate during
AF;
- the effects of dronedarone on subject-perceived AF burden and symptom severity as
reported by subjects using the Atrial Fibrillation Severity Scale (AFSS);
- the incidence of electrical cardioversion (or overdrive pacing) during treatment;
- the safety of dronedarone.