Effects of Ethanol on Oxycodone Pharmacokinetics in Healthy Volunteers

• Status: Completed
• Trial end date: 2014-08-01
• Target enrollment: 0
• Participant gender: All

Summary

To Estimate Bioavailability Of 40 Mg Doses Of Pf-00345439 Formulation K Under Fasting Conditions with 40% Ethanol Compared with Water in Healthy Volunteers

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Pain Therapeutics
• Treatments: Ethanol; Naltrexone; Oxycodone

Criteria

Inclusion Criteria:

• Healthy volunteers

• History of moderate alcohol consumption

• Total body weight exceeding 64 kg

Exclusion Criteria:

• Evidence or history of clinically significant disease.

• Positive urine drug test

• History of alcoholism or heavy alcohol consumption