Purpose of the study will be to evaluate the effects of the s.c. administration of 300 IU of
FSH in 16 healthy males. The endothelial function will be evaluated by the measurement with
ecographic approach of the flow mediated dilation (FMD) of the brachial artery. The FMD will
be measured before and 6, 12, 24 or 48 hours after FSH or placebo adiministration in the same
subjects studied 2 weeks apart. The results will help to clarify whether perturbation of FSH,
similar to the one observed in women after the menopause, affect endothelial function.