Overview

Effects of Flavors on Nicotine Reinforcement in Smokers

Status:
Completed
Trial end date:
2019-01-31
Target enrollment:
Participant gender:
Summary
To examine the acute reinforcing effects of menthol, a fruit flavor (green apple) or a fruit flavor plus menthol, alone or in combination with nicotine in smokers. Flavors will be administered by inhalation via electronic cigarettes (e-cigarettes) and nicotine will be administered intravenously. The reinforcing drug effects will be measured with the drug effects questionnaire (DEQ).
Phase:
Early Phase 1
Details
Lead Sponsor:
Yale University
Collaborator:
National Institute on Drug Abuse (NIDA)
Treatments:
Menthol
Nicotine