Effects of Garlic Supplements on Drug Metabolism

• Status: Completed
• Trial end date: 2009-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will determine whether garlic supplements affect the way certain drugs are processed in the body.

• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Fred Hutchinson Cancer Research Center
• Collaborator: National Center for Complementary and Integrative Health (NCCIH)
• Treatments: Allicin; Allyl sulfide

Criteria

Inclusion Criteria:

• Body mass index (BMI) between 20 and 32

• Able to read and understand English

• MUST LIVE WITHIN THE SEATTLE, WA AREA.

Exclusion Criteria:

• Current use of herbal medicines other than oral contraceptives

• History of cardiopulmonary, liver, renal or endocrine disease

• Allergy or sensitivity to any of the drugs that will be used in the probe cocktails or the garlic supplements

• Daily consumption of vegetables with a high allium content, including garlic, shallots, leeks, and chives

• Pregnancy or breastfeeding