Overview

Effects of Gastric pH on the Pharmacokinetics of Atazanavir

Status:
Completed
Trial end date:
2014-01-01
Target enrollment:
Participant gender:
Summary
The goal of this study is to evaluate the ability of a natural supplement (betaine hydrochloride) to affect the absorption of atazanavir in healthy volunteers. The investigators predict that betaine hydrochloride will increase the absorption of atazanavir in volunteers pre-treated with proton-pump inhibitors (PPIs).
Phase:
Phase 1
Details
Lead Sponsor:
University of California, San Francisco
Treatments:
Atazanavir Sulfate
Betaine
Rabeprazole
Ritonavir