Effects of Ginger on Nonalcoholic Fatty Liver Disease in T2DM

• Status: Completed
• Trial end date: 2020-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators want to evaluate the effects and safety of ginger in treatment of nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2DM).

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shiraz University of Medical Sciences

Criteria

Inclusion Criteria:

• Controlled type 2 diabetes mellitus (HbA1c<7%)

• Age: 20-65 years

• Body mass index: 18-35 kg/m2

• Serum ALT level: >60 U/Lit. in males, >38 U/Lit. in females

• Grade >=2 fatty liver in liver sonography

Exclusion Criteria:

• Pregnancy

• Acute or chronic liver failure

• Acute or chronic renal failure

• Autoimmune or viral hepatitis

• Wilson's disease

• Alcoholism

• Malignancy

• Hypothyroidism or hyperthyroidism

• Drug used in last three months: OCP, vitamin E, ursodeoxycholic acid, glucocorticoids.