Effects of Goal-directed Fluid Therapy on Post-operative Outcomes in Children Undergoing Scoliosis Repair

• Status: Terminated
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Surgery for scoliosis correction, the abnormal curvature of the spine, is a major procedure often undertaken in adolescents. In adult anesthesia, there is a large volume of literature debating how to optimize fluids administered during surgery, as both too much fluid and too little fluid are associated with worse outcomes. The investigators will compare fluid administration based on the measured amount of blood pumped by the heart during each heart beat (goal-directed therapy), against standard anesthetic management. The main outcomes are a) post-surgical kidney dysfunction, b) prevalence of intraoperative hypotension, c) volumes of administered fluids, and d) length of hospitalization.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of British Columbia
• Treatments: Plasma-lyte 148

Criteria

Inclusion Criteria:

• Patients undergoing scoliosis repair

• ASA physical status classification system (ASA) I-III

Exclusion Criteria:

• Pre-existing chronic kidney disease

• Oropharyngeal disease, e.g. pharyngitis

• Esophageal disease, e.g. heartburn, esophageal varices or hiatus hernia.

• Coagulopathy

• Scheduled for two stage procedures