Effects of Goal-directed Fluid Therapy on Post-operative Outcomes in Children Undergoing Scoliosis Repair
Status:
Terminated
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
Surgery for scoliosis correction, the abnormal curvature of the spine, is a major procedure
often undertaken in adolescents. In adult anesthesia, there is a large volume of literature
debating how to optimize fluids administered during surgery, as both too much fluid and too
little fluid are associated with worse outcomes. The investigators will compare fluid
administration based on the measured amount of blood pumped by the heart during each heart
beat (goal-directed therapy), against standard anesthetic management. The main outcomes are
a) post-surgical kidney dysfunction, b) prevalence of intraoperative hypotension, c) volumes
of administered fluids, and d) length of hospitalization.