Effects of Green Propolis Extract (EPP-AF) on Inflammation in Hemodialysis Patients.

• Status: Unknown status
• Trial end date: 2020-01-30
• Target enrollment: 0
• Participant gender: All

Summary

End-stage chronic kidney disease is associated with the condition of chronic inflammation. Patients on hemodialysis are known to be predisposed to several factors that predispose to inflammation: dialysis membranes, central venous catheters, oxidative stress, fluid overload, sodium overload, uraemic toxins. Propolis, a natural resin produced by bees from plant materials, has anti-inflammatory, immunomodulatory, and anti-oxidant properties. The aim of this study was to evaluate the impact of Brazilian green propolis extract on inflammation in hemodialysis patients.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Sao Paulo General Hospital
• Collaborators: Alagoas State University of Health Science , Maceió , Brazil.; Hospital Sao Rafael
• Treatments: Propolis

Criteria

Inclusion Criteria:

• Age over 18 years;

• Male or female on hemodialysis for at least 1 month.

Exclusion Criteria:

• Pregnant Woman;

• Carriers of active neoplasms;

• Patients undergoing kidney transplantation during the study;

• Infection during the study;

• Patients who underwent parathyroidectomy during the study;

• Patient using immunosuppressive drugs;

• Allergy to propolis or any of its components;