Effects of Gum Arabic on Metabolic Syndrome Parameters in Postmenopausal Women

• Status: Active, not recruiting
• Trial end date: 2022-12-20
• Target enrollment: 0
• Participant gender: Female

Summary

Gum Arabic ingestion has been proved to decrease some of the inflammatory markers in some metabolic diseases that have an inflammatory background. Nevertheless, the mechanism/s by which it does so is uncertain. This study is targeting one of the postulated molecular mechanisms at genetic level that may help to understand how Gum Arabic exerts its effect .The effects of GA on Nuclear Factor Kappa Beta, P38 Mitogen Activated Protein (MAP) Kinase levels, and on the expression of inflammatory cytokines genes are going to be assessed in postmenopausal females with Metabolic Syndrome.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Khartoum
• Collaborator: Ministry of Higher Education and Scientific Research, Republic of Sudan

Criteria

Inclusion Criteria:

• Inclusion criteria Females Menopause Metabolic syndrome based on Adult panel II criteria Signed/verbal consent to participate

Exclusion Criteria:

• Exclusion criteria

1. Patients with mental or physical disability

2. Use of corticosteroids or any other drug that affects body weight

3. History of Gum Arabic (GA) allergy

4. Chronicrenal or liver disease

5. Chronocinflammatory diseases

6. History of CVA or MI Participants will be asked to maintain their habitually daily diet and level of activity during the period of the study and to continue any previously prescribed medication.