Effects of Hemofiltration and Mannitol Treatment on Cardiopulmonary-Bypass Induced Immunosuppression
Status:
Unknown status
Trial end date:
2004-11-01
Target enrollment:
Participant gender:
Summary
After cardiac surgery with cardiopulmonar bypass, the LPS-stimulated cytokine response has
been previously shown to be depressed. Therefore, in this trial the hypothesis was tested,
whether simple immunomodulting interventions like the i.v. adminstration of mannitol of
hemofiltration during cardipulmonary bypass can attenuate this immunosuppressing effect.