This study will examine whether hesperidin, a major component of citrus fruits, affects how
the body responds to insulin in healthy and obese people. Laboratory studies suggest that
hesperidin treatment lowers blood pressure, lowers blood sugar and increases blood flow. This
study will see if hesperidin improves insulin resistance or insulin's effects on blood flow
in people with insulin resistance.
Healthy normal weight or overweight people between 21 and 65 years of age may be eligible for
this study. Participants are randomly assigned to take hesperidin or a placebo (inactive
dummy pill ) for a 4-week treatment phase.
Phase:
Phase 2
Details
Lead Sponsor:
University of Maryland University of Maryland, Baltimore