Effects of Hydration to Prevent Contrast Induced Nephropathy in PCI for ST-elevation Myocardial Infarction.

• Status: Completed
• Trial end date: 2010-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to test the efficacy of low versus high volume hydration and two different solutions (sodium chloride versus sodium bicarbonate) in preventing contrast induced nephropathy (CIN) in ST elevation myocardial infarction (STEMI) patients undergoing primary PCI.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Arcispedale Santa Maria Nuova-IRCCS
• Collaborator: Azienda Sanitaria Ospedaliera
• Treatments: Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Age > 18 years of years

• Chest pain lasting at least 30 minutes, non responsive to nitrates, associated to ST elevation of at least 0.2 mV on surface ECG in two or more contiguous leads or to new left bundle branch block.

• Informed consent

Exclusion Criteria:

• Chronic hemodialytic or peritoneal treatment

• Coronary anatomy unsuitable for PCI

• Need of emergency coronary artery by-pass grafting

• Post-anoxic coma

• Pregnancy