Effects of Intensive Systolic Blood Pressure Lowering Treatment on Out-of-office Blood Pressure - an Ancillary Study to Effects of Intensive Systolic Blood Pressure Lowering Treatment in Reducing RIsk of Vascular evenTs (ESPRIT) Study

• Status: Not yet recruiting
• Trial end date: 2023-09-30
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to evaluate the effect of intensive treatment (a target clinic based systolic blood pressure(BP) <120mmHg) on 24-hour ambulatory blood pressure and home blood pressure, as well as the effect on White-coat uncontrolled hypertension and masked uncontrolled hypertension, compared with standard treatment (a target clinic based systolic BP <140mmHg).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: China National Center for Cardiovascular Diseases
• Collaborator: Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, People's Republic of China

Criteria

Inclusion Criteria:

1. eligible for the follow up of the main study;

2. content to participate in the sub-study.

Exclusion Criteria:

1. frequently working during night-time;

2. the non - dominant arm could not wear 24-hour ambulatory blood pressure monitoring due to radiation therapy or physical impairment;

3. keep engaged in out-door activities of high physical intensity, e.g. farming or porter, etc.;

4. life expectancy is less than 1 year; such as diagnosed with heart failure, cancer, or end-stage renal disease;

5. the difference of clinical systolic pressure between upper arms was more than 10 mmHg;

6. unable to use smart-phone to upload family blood pressure monitoring data.