Effects of Intravenous Lidocaine on Transperitoneal Laparoscopic Urological Surgery
Status:
Completed
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
Effective perioperative analgesia is the key to postoperative rehabilitation. An intriguing
body of evidence suggests that short-term administration of intravenous lidocaine may produce
pain relief that far exceeds both the duration of infusion and the half-life of the drug.
When pain relief is provided, concomitant anal-gesic medication can be reduced, side effects
from pain relieving medication minimized with a potential for a more rapid postoperative
recovery and less complications. IV application of lidocaine should de-crease the duration of
bowel dysfunction. We hypothesise that i.v. application of lidocaine in a standard
antiarrythmic dose can significantly improve acute rehabilitation after laparoscopic
urological surgery and so shorten the hospital stay (primary outcome). We expect that the
intraoperative inflammatory response can significantly be reduced.