Effects of Iron on Exercise Capacity During Hypoxia
Status:
Completed
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
During alveolar hypoxia, for example at high altitude or in patients with respiratory
disease, there is evidence to suggest that hypoxia-induced pulmonary hypertension might limit
exercise performance. Intravenous iron supplementation has recently been shown to reverse
pulmonary hypertension in healthy humans at high altitude, and to prevent pulmonary
hypertension in volunteers exposed to hypoxia at sea level. The investigators hypothesized
that intravenous iron supplementation would enhance exercise capacity during alveolar
hypoxia.