Effects of Low Dose Ketamine Given at Induction of Anesthesia on Postoperative Mood in Patients With Depressive Symptoms
Status:
Terminated
Trial end date:
2016-09-01
Target enrollment:
Participant gender:
Summary
Ketamine has been shown to have an antidepressant effect when given intravenously in doses of
2mg/kg. Ketamine is used as a standard induction drug during general anesthesia. It is known
in this instance to decrease postoperative pain. No one has studied whether or not ketamine
when given in doses used during general anesthesia (0.5mg/kg intravenous) has an
antidepressant effect on surgical patients who suffer from depression. The study is designed
to determine whether or not a small dose of ketamine when given at the induction of
anesthesia could have an antidepressant effect on surgical patients with depression.
Phase:
N/A
Details
Lead Sponsor:
The University of Texas Health Science Center at San Antonio