Effects of Lubiprostone on Small Bowel and Colonic Bacteria: A Correlation Study With Segmental and Whole Gut Transit
Status:
Completed
Trial end date:
2011-05-01
Target enrollment:
Participant gender:
Summary
Patients with constipation often have bloating and abdominal distension. It is unclear if
this is related to intestinal bacteria. Hypothesis: treatment for constipation may reduce
small bowel and colon bacteria colonization, a change in the balance of stool microorganisms,
and improve the symptoms of dyspepsia and constipation.