Effects of Marijuana on Neuropathic Pain and Spasticity in Spinal Cord Injury Patients

• Status: Enrolling by invitation
• Trial end date: 2024-06-30
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical trial is to compare effects of marijuana or cannabis on neuropathic pain and spasticity in spinal cord injury patients. The main question is: Does the cannabis product from KhonKaen University reduce neuropathic pain and spasticity in spinal cord injury patients? The research design is a crossover study. The participants will be randomly into 2 groups: group 1 and group 2. The participants received either cannabis or placebo for 2 weeks. After completing treatment, participants were swapped to the other group for 2 weeks, a wash-out period is 2 weeks. The outcome measurements are pain and spasticity.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Khon Kaen University

Criteria

Inclusion Criteria:

• Spinal cord injury more than 6 months

• Neuropathic pain

• Pain score > 3

• Do not response to standard medical treatment

• Given inform consent

Exclusion Criteria:

• Allergy to cannabis

• Unstable cardiovascular and pulmonary diseases

• Chronic kidney and liver diseases

• Psychological disease

• Pregnancy or breastfeeding