Overview

Effects of Myo-inositol in Women With Polycystic Ovary Syndrome

Status:
Recruiting

Trial end date:
2022-07-01

Target enrollment:
0

Participant gender:
Female

Summary

The study will be carried out at the hospital of the medical school of sao paulo (HC-FMUSP) and the goal is to compare the effects of the administration of myo-inositol in relation to the effects of metformin in women with Polycystic Ovary Syndrome and insulin resistance or glucose intolerance. Menstrual cycle, hyperandrogenism, chronic inflammatory process, carbohydrate metabolism, hepatic steatosis will be evaluated. In total, 60 women in the reproductive period, with a variable age between 18 and 36 years old will be recruited and randomized in two groups: intervention- myo-inositol for 6 months, control group will use metformin also for 6 months.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

University of Sao Paulo General Hospital

Treatments:

Inositol
Metformin

Criteria

Inclusion Criteria:

- Women aged 18 to 36 with diagnosis of PCOS and insulin resistance or glucose
intolerance.

Exclusion Criteria:

- Previous use of any hormonal treatment in the past three months;

- Other causes of anovulation;

- Gynecological or other associated conditions (endometriosis, adenomyosis or diabetes
mellitus);

- FSH (Follicle Stimulating Hormone) > 15 Ul / L (2nd to 5th day of the cycle);

- Beta-hcG (human chorionic gonadotropin) positive (pregnancy).