Effects of N-acetylcysteine on Low T3 Syndrome

• Status: Completed
• Trial end date: 2013-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The propose of this study is to determine whether N-acetylcysteine is effective in reversing the changes in thyroid hormones seen in critical illness, known as the low T3 syndrome.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Federal University of Rio Grande do Sul
• Collaborators: Hospital de Clinicas de Porto Alegre; Programa de pós-graduação em endocrinologia
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

• diagnosis of acute myocardial infarction with less than 12 hours of evolution

• reperfusion therapy (primary angioplasty)

Exclusion Criteria:

• Thyroid disease

• Chronic renal disease with renal replacement therapy

• hepatic insufficiency

• immunosuppression