Effects of Nitroglycerin Versus Labetalol on Tissue Perfusion During Deliberate Hypotension

• Status: Completed
• Trial end date: 2019-05-25
• Target enrollment: 0
• Participant gender: All

Summary

Deliberate hypotension is used to provide bloodless field during endoscopic sinus surgery; however, hypotension might impair perfusion of vital organs. The aim of this work is to compare the impact of nitroglycerin and labetalol on peripheral perfusion when used for induction of deliberate hypotension

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Labetalol; Nitroglycerin

Criteria

Inclusion Criteria:

• Adult male or female patients

• 18-45 years

• ASA physical status I-II

• scheduled for FESS operations

Exclusion Criteria:

• uncontrolled hypertension

• cerebrovascular disorders

• coagulation disorders

• cardiovascular diseases

• renal impairment

• liver impairment

• history of allergic reaction to any of the study medications