Effects of Onion Peel Extract on Endothelial Function

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Acute or chronic intake of polyphenol-rich foods has been reported to improve endothelial function. Quercetin, found abundantly in onion, is a potent antioxidant flavonoid. This study was designed to investigate whether consumption of onion peel extract (OPE) improves endothelial function in healthy overweight and obese subjects.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Kyunghee University Medical Center
• Collaborator: Kyunghee University

Criteria

Inclusion Criteria:

• age 20 to 60 years

• BMI >23 kg/m2

• abdominal circumference > 90 cm in males or >85 cm in females

Exclusion Criteria:

• hypertension (>140/90 mmHg),

• diabetes

• any cardiovascular disease,

• kidney disease,

• thyroid disease

• cerebrovascular disease

• liver disease (bilirubin level >2 mg/dl)

• pregnancy