Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis

• Status: Recruiting
• Trial end date: 2024-01-30
• Target enrollment: 0
• Participant gender: All

Summary

As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis. This study aims to add to the existing body of research around aloe vera juice and its effects on oral mucositis and esophagitis. The intention is to determine whether aloe vera juice should be considered as part of standard treatment.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Thompson Cancer Survival Center
• Treatments: Sucralfate

Criteria

Inclusion Criteria:

• must have signed and dated an IRB approved consent form that conforms to federal and institutional guidelines

• Age >/= 18 years

• Confirmed lip, oral cavity, hard palate, tongue, tonsil, pharyngeal, neck, esophageal, mediastinal, and/or chest wall cancers

• Women of child-bearing potential and men must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry and for the duration of study participation.

• Men treated or enrolled on this protocol must agree to use adequate contraception prior to the study, for the duration of study participation.

Exclusion Criteria:

• Patients who are not on concurrent chemotherapy and radiation.

• History of allergic reactions attributed to compounds of similar chemical or biologic composition to aloe vera juice.

• Patients with psychiatric illness/social situations that would limit compliance with study requirements.

• Pregnant women or women who are breastfeeding