Effects of Oral Glucose and Teduglutide on Plasma Lipoproteins
Status:
Recruiting
Trial end date:
2022-05-01
Target enrollment:
Participant gender:
Summary
Some of the fat (triglyceride) from the food humans eat gets stored in the bowel. This
triglyceride can then be released into the blood when another meal is consumed or in response
to hormones. How the gut hormone glucagon-like peptide-2 (GLP-2) and glucose release the
triglyceride from the gut is not known. The research team in this study is interested in
finding out how teduglutide (a degradation resistant form of GLP-2) ang glucose, given
together, release stored triglyceride from the gut by evaluating how blood lipoproteins
respond to teduglutide in healthy individuals.