Effects of Oxytocin on Negative Symptoms and Social Cognition in Schizophrenia and Its Possible Mechanisms
Status:
Completed
Trial end date:
2020-03-31
Target enrollment:
Participant gender:
Summary
The purpose of this study was to investigate the effects of oxytocin on negative symptoms and
social cognitive task performance in schizophrenia. The investigators conducted a randomized,
placebo-controlled trial testing the effects of twice daily intranasal oxytocin treatment for
14 days on psychotic symptoms and social cognition in patients with schizophrenia. The
investigators hypothesize that PANSS scores will decline significantly and several social
cognition measures will improved significantly or nearly significantly in oxytocin but not
placebo recipients.