Effects of Perioperative B&O Suppositories on Post-op Pain and Morphine Use After Laparoscopic Prostatectomy

• Status: Completed
• Trial end date: 2009-07-01
• Target enrollment: 0
• Participant gender: Male

Summary

This study is evaluating the effect of a Belladonna and Opium suppository administered intraoperatively on post operative pain after laparoscopic radical prostatectomy for prostate cancer. This is a blinded randomized study. 50% of patients will receive the suppository, 50% of patients will not. Neither you or your surgeon will know which group you are in.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Benaroya Research Institute
• Collaborators: Virginia Mason Hospital/Medical Center; Virginia Mason Medical Center, Departments of Urology and Anesthesiology
• Treatments: Morphine; Opium

Criteria

Inclusion Criteria:

• Patients scheduled for laparoscopic radical prostatectomy at Virginia Mason, who do not have chronic pain or allergies to opioid analgesics are eligible for this study.

Exclusion Criteria:

• Women are excluded due to the absence of a prostate.

• Children are excluded due to the absence of prostate cancer in this group.

• Patients meeting any of the following will not be eligible for the study:

• Patients at risk for complications from anticholinergic agents including those with a history of glaucoma, bronchial asthma, convulsive disorder, or high risk for delirium

• History of previous allergies or adverse reactions to belladonna and opium and/or opioid analgesics

• History of chronic pain or chronic use of opioid and nonopioid analgesics

• History of alcohol or opioid dependency/abuse within last three months