Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery
Status:
Terminated
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to determine the opiate sparing effects of intravenously
administered dexamethasone in outpatient knee surgery. Dexamethasone is a glucocorticoid with
well known antiemetic effects. However, the analgesic effects of dexamethasone have not been
adequately researched. Following surgery, patients are typically discharged home with PO
opiates to manage post-operative pain. The investigators believe that by using VAS (Visual
Analog Scale) for Pain the investigators can show that a single dose of dexamethasone can
reduce pain scales and opiate consumption post-operatively, on Post Operative Day (POD 1)
when compared to placebo.