Effects of Perioperative Systemic Ketamine on Development of Long-term Neuropathic Pain After Thoracotomy
Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
Lung surgery under thoracotomy is known to induce long-term pain which can be considered as
neuropathic in many patients concerned [1,2]. The suspected origin of neuropathy is a direct
traumatism of intercostal nerve(s) [3]. Among the possible preventive treatments that can be
administered during the initial aggression, ketamine [4,5] appears as the easiest to use, as
it is already commonly administered intra and postoperatively for improvement of analgesia
[6].