The purpose of this study is to determine how pioglitazone and aspirin affect platelets in
the blood of diabetic and non-diabetic subjects. Platelets are small cells in the blood that
help with blood clotting. Pioglitazone is a drug that is used to lower blood sugar and fats
by helping the body to use insulin correctly. Pioglitazone is presently used to treat
diabetes but has not been approved for non-diabetics. This study will determine whether
pioglitazone reduces the activity of platelets in people who are or are not also taking
aspirin.