Effects of Preoperative Gabapentin Versus Pregabalin on Shoulder Pain After Laparoscopic Cholecystectomy

• Status: Completed
• Trial end date: 2017-09-28
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to evaluate the effect of premedication with pregabalin or gabapentin versus placebo on postoperative shoulder pain after laparoscopic cholecystectomy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Faculty of Medicine, Sousse
• Treatments: Gabapentin; gamma-Aminobutyric Acid; Pregabalin

Criteria

Inclusion Criteria:

• uncomplicated laparoscopic cholecystectomy

• American Society of Anesthesiologists (ASA) status < 3

Exclusion Criteria:

• acute cholecystitis

• conversion to open cholecystectomy

• history of epilepsia, psychiatric disorders and cognitive impairment

• Pregnancy and breastfeeding

• allergy to pregabalin and/or gabapentin

• Chronic pain

• Chronic medication by corticosteroids, neuroleptics or non steroidal anti inflammatory drugs