Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical Patients
Status:
Recruiting
Trial end date:
2022-07-31
Target enrollment:
Participant gender:
Summary
This study is an ancillary (add-on) study to the clinical trial entitled "Effect of Nitric
Oxide in Cardiac Surgery Patients With Endothelial Dysfunction", which has Clinical
Trials.gov identifier NCT02836899. NCT02836899 trial randomizes cardiac surgical patients to
receive either Nitric Oxide (NO) or a placebo during and after cardiac surgery.
This ancillary study aims to assess the effects of Nitric Oxide on plasma reduction-oxidation
reactions of patients undergoing cardiac surgery requiring prolonged cardiopulmonary bypass.
Phase:
Phase 2
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborators:
Marrazzo, Francesco, M.D., Massachusetts General Hospital Spina, Stefano, M.D., Massachusetts General Hospital University of Southampton Zadek, Francesco, M.D., Massachusetts General Hospital