Effects of Propofol and Sevoflurane on Blood Folic Acid and Homocysteine Concentrations in Children

• Status: Unknown status
• Trial end date: 2018-10-30
• Target enrollment: 0
• Participant gender: All

Summary

To investigate the effect of sevoflurane and propofol on the concentrations of serum homocysteine and folic acid in children who received cochlear implant surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
• Treatments: Anesthetics; Folic Acid; Propofol; Sevoflurane; Vitamin B Complex

Criteria

Inclusion Criteria:

• children accepted cochlear implant surgery under general anesthesia

• no participate in any other trial up to 3 months before this study

• no acute infectious diseases, systemic diseases

• willing to participate in this study and sign the informed consent

Exclusion Criteria:

• unwilling to participate in this study

• with a history of serious liver or kidney dysfunction

• hemodynamic instability (etc. shock, blood pressure reduced by 30%)

• children with egg milk allergy

• children with a family history of malignant hyperthermia