Effects of Propofol-dexmedetomidine on Immune Function in Patients With Cancer Larynx

• Status: Completed
• Trial end date: 2016-10-30
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this prospective, randomized clinical study is to compare between propofol and isoflurane on perioperative immune cell populations and function in patients undergoing total laryngectomy surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Anesthetics; Dexmedetomidine; Isoflurane; Propofol

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists physical status I- III

• Scheduled for total laryngectomy.

Exclusion Criteria:

• Patients refusal.

• Morbid obese patients (body mass index >40 kg/m2).

• Allergy to local anesthetics agents used.

• Severely altered consciousness level.

• Psychiatric disorders.

• Severe or uncompensated cardiovascular disease.

• Severe renal disease.

• Severe hepatic disease.

• Severe endocrinal diseases.