Overview
Effects of Pulmonary Vasodilation Upon VA Coupling in Fontan Patients
Status:
Withdrawn
Withdrawn
Trial end date:
2017-12-01
2017-12-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The study involves documenting the effects of inhaled nitric oxide upon ventricular-arterial coupling in patients with congenital heart disease and passive pulmonary blood flow. Consenting patients undergoing a clinically-indicated cardiac catheterization will be given inhaled nitric oxide for 10 minutes while intraventricular pressure-volume analysis will be make via conduction catheters.Phase:
Phase 3Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
University of California, San FranciscoTreatments:
Nitric Oxide
Criteria
Inclusion Criteria:- All consecutive patients with single ventricle hearts having passive pulmonary blood
flow presenting to the cardiac catheterization laboratory for clinically indicated
cardiac catheterization.
Exclusion Criteria:
- Patients with coarctation of the aorta or known bilateral femoral arterial obstruction
- Patients with known severe systemic venous/Fontan obstruction
- Patients already receiving sildenafil or other vasodilator therapy