Overview

Effects of Ranolazine on Coronary Microvascular Dysfunction in Patients With Hypertrophic Cardiomyopathy

Status:
Completed
Trial end date:
2020-03-06
Target enrollment:
Participant gender:
Summary
To demonstrate the efficacy of ranolazine in improving coronary microvascular and diastolic dysfunction in patients affected by HCM evaluating changes in maximum (i.e. during dipyridamole-induced coronary vasodilatation) myocardial blood flow (MBF) measured by PET at baseline and after 4 months of treatment with ranolazine in patients with non obstructive HCM.
Phase:
Phase 2
Details
Lead Sponsor:
IRCCS San Raffaele
Collaborator:
Menarini International Operations Luxembourg SA
Treatments:
Ranolazine