Effects of Recombinant Human Thrombopoietin on Platelet Levels in ICU Patients

• Status: Not yet recruiting
• Trial end date: 2023-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The incidence of thrombocytopenia in ICU patients with severe illness ranged from 8.3% to 67.6%, and ranged from 14% to 44% during ICU treatment.Severe patients with thrombocytopenia also have significantly increased bleeding events and blood transfusions, and even a significantly increased risk of death.This study examines whether elevated platelets benefit patients with pneumonia

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nanfang Hospital of Southern Medical University
• Collaborators: Shenzhen Hospital of Southern Medical University; The Second People's Hospital of GuangDong Province; The Third Affiliated Hospital of Southern Medical University

Criteria

Inclusion Criteria:

• Clinical diagnosis of pneumonia (community acquired pneumonia, hospital acquired pneumonia or ventilator associated pneumonia);

• Voluntarily signed informed consent;

• ≥18 years old;

• Platelet count ≤75×109/L

Exclusion Criteria:

• A history of hematopoietic stem cell transplantation or solid organ transplantation such as liver, kidney or lung;

• Hematological malignancy;

• Immune thrombocytopenia, such as SLE, ITP, TTP, etc.

• The length of stay in ICU is less than 24h;

• Pregnant or lactation patients;