Effects of Restrictive Fluid Strategy on Postoperative Oliguric Pancreatic Surgery Patients

• Status: Unknown status
• Trial end date: 2021-06-30
• Target enrollment: 0
• Participant gender: All

Summary

Reduced urinary output is a common postoperative issue for patients going through major surgery such as pancreatic surgery. Commonly this is treated by increasing fluid administration to the patients and sometimes also diuretics. However, overloading patients with fluid also have several risks and known complications. Studies have also shown that a short period of decreased urinary output in the postoperative period do not have an increased incidence of acute renal failure. The aim of our study is to investigate the difference in renal function and postoperative complications associated with fluid overload on these patients that are randomized to either receiving a fluid bolus directly when urinary output decreases or to await for a maximum of four hours to see if urinary output increases spontaneously.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Uppsala University

Criteria

Inclusion Criteria:

• Patients going through pancreatic surgery.

Exclusion Criteria:

• If not oliguric (urinary output <0,5 mls/kg/h) during their stay in the postoperative department

• Hemodynamic instability (the need for >0,1 microgram/kg/min of norepinephrine to keep an acceptable mean arterial pressure based on the patients starting mean arterial pressure).

• Patients that do not want to be a part of the study.

• <18 years old