Effects of St. John's Wort on the Oral Contraceptive Hormone Levonorgestrel

• Status: Completed
• Trial end date: 2008-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study will determine the effects of St. John's wort, a common herbal remedy, on metabolism of the female contraceptive hormone levonorgestrel.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Utah
• Collaborator: National Center for Complementary and Integrative Health (NCCIH)
• Treatments: Levonorgestrel

Criteria

Inclusion Criteria:

• Body mass index (BMI) between 20 and 25

• Regular menstrual cycles for at least 3 months prior to study entry

Exclusion Criteria:

• Current use of foods, herbs, vitamins, over-the-counter supplements, or any medications that could alter pharmacokinetics of other drugs

• Medical contraindications to the use of contraceptives