Effects of Statin Therapy on Vascular Properties and Outcomes in Diastolic Heart Failure Patients
Status:
Terminated
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
The study is designed to define the underlying vascular abnormalities present in patients
with diastolic heart failure and test the effect of a therapy aimed at vascular
abnormalities. This study is designed to investigate the effects of therapy with atorvastatin
in subjects with diastolic heart failure to improve abnormalities of vascular and myocardial
structure and function, with particular emphasis on arterial stiffness and endothelial
dysfunction.