Effects of Statins on Lower Extremity Arterial Function Assessed by Magnetic Resonance Imaging
Status:
Terminated
Trial end date:
2012-07-01
Target enrollment:
Participant gender:
Summary
Cholesterol-lowering drugs called statins improve the functioning of the endothelium, and
help prevent heart disease. The investigators are testing whether statins improve endothelial
function more in the arteries that have worse endothelium to begin with. One of the functions
of the endothelium is to help control how blood vessels dilate (expand) or contract (narrow)
in different situations. This affects how blood flows through those vessels. Magnetic
resonance imaging (MRI) can be used to evaluate endothelial function in the arms and legs
noninvasively.