Effects of Succinylcholine on Nonintubated Thoracoscopic Surgery

• Status: Unknown status
• Trial end date: 2019-07-31
• Target enrollment: 0
• Participant gender: All

Summary

A safe and effective surgical environment is important for nonintubated thoracoscopic surgery. The investigators hypothesize that mini-dose succinylcholine can induce ultra-short period of apnea, by which the ventilatory responses to open pneumothorax were abolished and may facilitate rapid and satisfying collapse of the operated lung during nonintubated thoracoscopic surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Taiwan University Hospital
• Treatments: Succinylcholine

Criteria

Inclusion Criteria:

• Adults patients with lung tumors and elective for unilateral thoracoscopic surgery.

Exclusion Criteria:

• Over weighted, body mass index > 26 kg/m2.

• Previous thoracic surgery on the attempted operative side.

• Hypoventilation syndrome requiring positive pressure ventilatory support or oxygen at home.

• Relevant systemic disease, including heart failure, liver failure, renal failure with an American Society of Anesthesiologists (ASA) class above 3.

• Difficult airway management.

• Pregnancy.

• Contraindications for succinylcholine, including family history of suspicious malignant hyperthermia, hyperkalemia, or other neuromuscular diseases.